Cancer genes — processed genes — jumping genes

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Jumping and Non-Jumping Genes

The term ‘horizontal transfer (HT)’ refers to the transfer of genetic material between two reproductively isolated organisms. HT is thought to occur rarely in eukaryotes compared to vertical inheritance, the transmission of DNA from parent to offspring. In a recent study we have provided evidence that a family of DNA transposons, called SPACE INVADERS or SPIN, independently invaded horizontally...

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Nothing is more Australian than kangaroos. But these marsupials—along with a variety of others including the Tasmanian devil—have ancient roots in South America, a new study suggests. Exactly how these various marsupials, both living and extinct, are related has been murky. There are marsupials found today in both Australia and the Americas, with the opossum the most familiar to Americans. Some...

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On jumping genes and other things

EMBO Reports (ER): Many thanks for agreeing to talk with EMBO Reports about the fascinating topic of transposable element activity in the human genome. First of all, how did you become interested in this phenomenon? Fred Gage (FG): I first became aware of transposable elements approximately 14 years ago, when I was studying a gene that modifies fibroblast growth factor (FGF) transcription. This...

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The main objective of cancer molecu~ar biology is to identity cancer genes. ~espite fierce efforts, this objective has still not been met [1-3]. As yet the only known cancer genes are the transformin~ one g~n.e~ of retroviruses. Typically these VIruses InItiate and maintain cancers with autonomous transforming genes that ~re domina~t in susceptible cells [5]. The dIsc~very of ~Ingle gene determ...

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ژورنال

عنوان ژورنال: Nature

سال: 1982

ISSN: 0028-0836,1476-4687

DOI: 10.1038/296393a0